Composition (per unit)

Succinic Acid 1.8%, PDRN 1%, Hyaluronic Acid 1%, Copper Tripeptide
and Oligopeptide 0.5%

AMBARÉ is an advanced skin booster crafted with a bioactive synergy of noncrosslinked Hyaluronic Acid, Succinic Acid, PDRN, and regenerative peptides. It is designed to stimulate dermal regeneration, enhance skin texture, and restore the skin’s metabolic equilibrium. Its formulation integrates immediate effects—hydration, luminosity, and firmness—with long-term benefits, including collagen stimulation, enhanced elasticity, and tone homogenization. It targets the primary mechanisms of skin aging, diminishing inflammation, oxidative stress, and hyperpigmentation, while enhancing cell regeneration and maintaining water balance.

Mechanism of action.

Antioxidant Properties of Succinic Acid:
It neutralizes free radicals and diminishes cellular oxidative stress. Its capacity to chelate copper ions inhibits tyrosinase activity, thereby obstructing melanin production and diminishing hyperpigmentation.

  • Stimulation of Cellular Metabolism:

Succinic acid plays a crucial role in the Krebs cycle, facilitating ATP production and cellular regeneration. It enhances dermal metabolism, oxygenation, and tissue regeneration.

  • Dermal Regeneration and Restructuring (PDRN):

It activates adenosine A2A receptors, promoting fibroblast proliferation, collagen and elastin synthesis, and cellular DNA repair. It enhances microcirculation, promotes angiogenesis, and facilitates lymphatic drainage

Hydrating and Firming Properties (Hyaluronic Acid):

It occupies extracellular spaces, retains moisture, and rejuvenates the skin’s
turgor and elasticity, establishing an ideal environment for the biostimulating
effects of the other components.

  • Biomimetic peptides facilitate cell signaling, enhance tissue regeneration,
    and augment skin cohesion and firmness.

Instructions

Skin rejuvenation and profound revitalization. Enhances skin texture, tone, and luminosity.
Diminution of fine lines and superficial wrinkles. Diminution of hyperpigmentation and blemishes. Restoration of dermal hydration and cellular metabolic equilibrium. Fatigued, dehydrated skin or skin exhibiting signs of photoaging.

Areas of Application:

Face, neck, décolletage, backs of hands, and other sun-exposed areas.

Technique:

Subdermal or supraperiosteal injection utilizing a 25-27G cannula or a
26-27G needle.
Small aliquots, fan technique, or threading.
Gentle massage following injection for uniform distribution.

Therapeutic sessions:

Three to five sessions with intervals of two to three weeks.

Adverse effects

Transient erythema, edema, or hematoma may manifest at the injection
site. These typically resolve spontaneously within a few days.

About Us

Evandré Pharma is a forward- thinking pharmaceutical and aesthetics company dedicated to advancing regenerative medicine. We specialize in high-quality dermal fillers, collagen inductors, peptides, and IV therapies, combining cutting-edge science with strict European standards. Our mission is to empower medical professionals with innovative solutions that deliver safety, efficacy, and natural results.


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